CHST5

Across TCGA cell cohorts, CHST5 mutation is significantly associated with the RNA expression of many other genes, with 585 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHST5-associated genes across cancer lineages are GAGE10, OR10H5, and GGA1. Each is linked with CHST5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHST5-to-partner and partner-to-CHST5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE10 grouped by CHST5-low versus CHST5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST5→partner) and Y-score (partner→CHST5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GAGE10 →	+0.055	+3.450	.007	.004	3	1
OVARY	OR10H5 →	+0.013	+3.990	<.001	.003	3	1
LARGE_INTESTINE	GGA1 →	+0.703	+3.212	.001	.006	3	1
LARGE_INTESTINE	DEPDC5 →	+0.672	+3.212	.001	.006	3	1
LARGE_INTESTINE	CBY1 →	+0.911	+3.299	<.001	.004	3	1
LARGE_INTESTINE	L3MBTL2 →	+0.747	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 585 associations by consensus.

GAGE10 by CHST5 expression — BLOOD_Leukemia

Explore this box plot interactively →