CHST4

Across TCGA patient cohorts, CHST4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,144 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CHST4-associated proteins across cancer lineages are PLEKHA7, MYO5C, and TJP3_S346. Each is linked with CHST4 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHST4-to-partner and partner-to-CHST4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHST4 versus PLEKHA7 in GBM, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST4→partner) and Y-score (partner→CHST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLEKHA7 →	+0.432	+0.551	.004	<.001	3	5
UCEC	MYO5C →	+0.615	+1.170	<.001	<.001	3	4
LSCC	TJP3_S346 →	+0.888	+0.962	<.001	<.001	3	4
OV	FCSK →	+0.380	+1.015	<.001	<.001	3	4
GBM	PAXBP1 →	+0.224	+0.767	<.001	<.001	3	3
OV	REXO4 →	-0.369	-1.319	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,144 associations by consensus.

CHST4 vs PLEKHA7 — GBM

Explore this scatter interactively →