CHST4

Across TCGA patient cohorts, CHST4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,964 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHST4-associated genes across cancer lineages are LRG1, SEMA6C, and PDZK1IP1. Each is linked with CHST4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHST4-to-partner and partner-to-CHST4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHST4 versus LRG1 in LSCC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST4→partner) and Y-score (partner→CHST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LRG1 →	+2.702	+0.890	.001	.005	3	3
LSCC	SEMA6C →	-1.938	-1.088	<.001	<.001	3	2
OV	PDZK1IP1 →	+3.198	+1.997	<.001	.001	3	2
LSCC	CXCL1 →	+3.819	+1.073	<.001	<.001	3	2
PDAC	GSTA2 →	+1.602	+0.679	.001	.002	3	2
LSCC	CXCL6 →	+3.516	+0.957	.008	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,964 associations by consensus.

CHST4 vs LRG1 — LSCC

Explore this scatter interactively →