CHST4

Across TCGA cell cohorts, CHST4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,473 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CHST4-associated GO terms across cancer lineages are Striated muscle atrophy, Regulation of dendritic cell apoptotic process, and Protein localization to plasma membrane. Each is linked with CHST4 in more than 7 cancer types. Because this analysis shows association rather than direction, both CHST4-to-partner and partner-to-CHST4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Striated muscle atrophy grouped by CHST4-low versus CHST4-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST4→partner) and Y-score (partner→CHST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Striated muscle atrophy →	+0.212	+0.462	<.001	.001	3	8
BREAST	Regulation of dendritic cell apoptotic process →	+0.800	+0.483	<.001	.001	3	7
STOMACH	Protein localization to plasma membrane →	+0.051	+0.982	.002	.008	3	7
LUNG_NSCLC_LUAD	Rho protein signal transduction →	+0.095	+0.781	<.001	<.001	2	7
BREAST	Antimicrobial peptide production →	+1.284	+0.470	<.001	.003	3	6
BREAST	Antimicrobial peptide biosynthetic process →	+1.284	+0.470	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,473 associations by consensus.

Striated muscle atrophy by CHST4 expression — BREAST

Explore this box plot interactively →