CHST2

Across TCGA patient cohorts, CHST2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,309 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHST2-associated genes across cancer lineages are ITPRIP, GPHN, and LGALS1. Each is linked with CHST2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHST2-to-partner and partner-to-CHST2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHST2 versus ITPRIP in GBM, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST2→partner) and Y-score (partner→CHST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ITPRIP →	+1.060	+0.807	<.001	.001	3	2
HNSC	GPHN →	-0.896	-1.010	.009	.001	3	2
GBM	LGALS1 →	+1.088	+0.770	.002	.001	3	1
GBM	SPRTN →	-0.396	-0.680	.002	.003	3	1
GBM	FMR1 →	-0.528	-0.611	<.001	.008	3	1
GBM	JADE3 →	-1.029	-0.695	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,309 associations by consensus.

CHST2 vs ITPRIP — GBM

Explore this scatter interactively →