CHST2

Across TCGA patient cohorts, CHST2 mutation is significantly associated with the RNA expression of many other genes, with 2,435 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHST2-associated genes across cancer lineages are RNA5SP146, RNU6-1026P, and DHX16. Each is linked with CHST2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHST2-to-partner and partner-to-CHST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP146 grouped by CHST2-low versus CHST2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST2→partner) and Y-score (partner→CHST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP146 →	+0.142	+1.747	.007	.007	3	3
TGCT	RNU6-1026P →	+0.411	+5.181	<.001	.006	3	2
COAD	DHX16 →	+0.334	+3.584	.006	.002	3	2
COAD	ZNF433-AS1 →	+0.399	+3.371	.002	.004	3	2
COAD	RN7SL638P →	+0.128	+3.053	.005	.007	3	2
COAD	RNU6ATAC17P →	+0.400	+2.402	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,435 associations by consensus.

RNA5SP146 by CHST2 expression — UCEC

Explore this box plot interactively →