CHST2

Across TCGA cell cohorts, CHST2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,283 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CHST2-associated GO terms across cancer lineages are Nucleoside diphosphate catabolic process, Potassium ion transport, and Potassium ion transmembrane transport. Each is linked with CHST2 in more than 9 cancer types. Because this analysis shows association rather than direction, both CHST2-to-partner and partner-to-CHST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside diphosphate catabolic process grouped by CHST2-low versus CHST2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST2→partner) and Y-score (partner→CHST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Nucleoside diphosphate catabolic process →	+0.113	+1.247	<.001	<.001	3	10
OVARY	Potassium ion transport →	-0.068	-1.496	.001	.003	3	9
OVARY	Potassium ion transmembrane transport →	-0.064	-1.099	.001	.008	3	9
OESOPHAGUS	Regulation of ubiquitin-dependent protein catabolic process →	+0.048	+0.865	.003	.005	3	9
BLOOD_Leukemia	Transcription preinitiation complex assembly →	+0.053	+1.688	<.001	<.001	3	9
OESOPHAGUS	Establishment of protein localization to organelle →	+0.054	+0.976	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,283 associations by consensus.

Nucleoside diphosphate catabolic process by CHST2 expression — SKIN

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