CHST15

Across TCGA cell cohorts, CHST15 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,013 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHST15-associated GO terms across cancer lineages are Release of cytochrome c from mitochondria, Protein lipidation, and Cellular response to platelet-derived growth factor stimulus. Each is linked with CHST15 in more than 11 cancer types. Because this analysis shows association rather than direction, both CHST15-to-partner and partner-to-CHST15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Release of cytochrome c from mitochondria grouped by CHST15-low versus CHST15-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST15→partner) and Y-score (partner→CHST15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Release of cytochrome c from mitochondria →	+0.174	+1.704	<.001	<.001	3	12
LIVER	Protein lipidation →	+0.150	+1.959	<.001	.006	2	12
OESOPHAGUS	Cellular response to platelet-derived growth factor stimulus →	+0.143	+1.672	<.001	<.001	3	10
LUNG_SCLC	Regeneration →	+0.098	+1.244	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Regulation of transforming growth factor beta3 production →	+0.255	+1.474	.006	<.001	3	10
BONE	Wound healing →	+0.151	+2.117	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,013 associations by consensus.

Release of cytochrome c from mitochondria by CHST15 expression — SKIN

Explore this box plot interactively →