CHST15

Across TCGA cell cohorts, CHST15 mutation is significantly associated with the RNA expression of many other genes, with 408 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHST15-associated genes across cancer lineages are CBY1, MCAT, and KDELR1. Each is linked with CHST15 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHST15-to-partner and partner-to-CHST15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by CHST15-low versus CHST15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST15→partner) and Y-score (partner→CHST15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.648	+3.299	.001	.004	3	1
LARGE_INTESTINE	MCAT →	+0.641	+3.212	.003	.006	3	1
LARGE_INTESTINE	KDELR1 →	+0.540	+3.212	.004	.006	3	1
LARGE_INTESTINE	SH3GL2 →	+1.518	+3.474	<.001	.003	3	1
LARGE_INTESTINE	FGF8 →	+0.321	+3.160	.002	.006	3	1
LARGE_INTESTINE	TRIM37 →	+0.823	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 408 associations by consensus.

CBY1 by CHST15 expression — LARGE_INTESTINE

Explore this box plot interactively →