CHST14

Across TCGA patient cohorts, CHST14 protein abundance is significantly associated with the RNA expression of many other genes, with 11,703 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHST14-associated genes across cancer lineages are NALCN, COL1A1, and PRRX1. Each is linked with CHST14 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHST14-to-partner and partner-to-CHST14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHST14 versus NALCN in PDAC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST14→partner) and Y-score (partner→CHST14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NALCN →	+0.530	+0.281	<.001	<.001	3	6
GBM	COL1A1 →	+1.877	+0.257	<.001	<.001	3	6
OV	PRRX1 →	+2.703	+0.733	<.001	<.001	3	6
BRCA	LOXL1 →	+1.268	+0.424	<.001	<.001	3	6
OV	TPM1 →	+0.728	+0.450	<.001	<.001	3	6
OV	TGFB1I1 →	+0.813	+0.449	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,703 associations by consensus.

CHST14 vs NALCN — PDAC

Explore this scatter interactively →