CHST14

Across TCGA cell cohorts, CHST14 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,913 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CHST14-associated GO terms across cancer lineages are Dermatan sulfate proteoglycan biosynthetic process, Response to UV, and Dermatan sulfate proteoglycan metabolic process. Each is linked with CHST14 in more than 14 cancer types. Because this analysis shows association rather than direction, both CHST14-to-partner and partner-to-CHST14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dermatan sulfate proteoglycan biosynthetic process grouped by CHST14-low versus CHST14-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST14→partner) and Y-score (partner→CHST14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Dermatan sulfate proteoglycan biosynthetic process →	+0.155	+1.510	<.001	.001	3	15
OESOPHAGUS	Response to UV →	+0.039	+0.766	.004	.002	3	14
LUNG_NSCLC_LUSC	Dermatan sulfate proteoglycan metabolic process →	+0.165	+1.775	.005	.003	2	15
OESOPHAGUS	Cell division →	+0.086	+0.888	.002	.009	3	14
BONE	Collagen biosynthetic process →	+0.224	+1.134	<.001	<.001	3	13
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.184	+0.988	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,913 associations by consensus.

Dermatan sulfate proteoglycan biosynthetic process by CHST14 expression — BONE

Explore this box plot interactively →