CHST13

Across TCGA patient cohorts, CHST13 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHST13-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, p62 Lck ligand, and 4E-BP1. Each is linked with CHST13 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHST13-to-partner and partner-to-CHST13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-a-Tubulin-Lys40 grouped by CHST13-low versus CHST13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST13→partner) and Y-score (partner→CHST13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.529	+2.817	.047	.036	2	2
UCEC	p62 Lck ligand →	+0.451	+3.009	.008	.019	3	1
UCEC	4E-BP1 →	+0.322	+3.029	.023	.018	2	1
UCEC	Di-Ras3 →	-0.179	-3.321	.021	.010	2	1
UCEC	ERK2 →	+0.280	+3.321	.005	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Acetyl-a-Tubulin-Lys40 by CHST13 expression — UCEC

Explore this box plot interactively →