CHST13

Across TCGA cell cohorts, CHST13 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHST13-associated genes across cancer lineages are SLC5A8, SLC35G3, and SYCN. Each is linked with CHST13 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHST13-to-partner and partner-to-CHST13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A8 grouped by CHST13-low versus CHST13-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST13→partner) and Y-score (partner→CHST13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SLC5A8 →	+0.070	+4.906	<.001	.006	3	1
BLOOD_Leukemia	SLC35G3 →	+0.075	+4.874	<.001	.002	3	1
BLOOD_Leukemia	SYCN →	+0.035	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR4N4 →	+0.052	+4.874	<.001	.002	3	1
BLOOD_Leukemia	PRR30 →	+0.011	+5.269	.005	<.001	3	1
BLOOD_Leukemia	OR10T2 →	+0.681	+4.276	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

SLC5A8 by CHST13 expression — OESOPHAGUS

Explore this box plot interactively →