CHST11

Across TCGA patient cohorts, CHST11 protein abundance is significantly associated with the RNA expression of many other genes, with 5,410 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHST11-associated genes across cancer lineages are PGAP4, CHST15, and SPNS3. Each is linked with CHST11 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHST11-to-partner and partner-to-CHST11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHST11 versus PGAP4 in LSCC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST11→partner) and Y-score (partner→CHST11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PGAP4 →	-1.130	-0.432	.001	.001	3	3
HNSC	CHST15 →	+1.218	+0.531	<.001	.001	3	3
GBM	SPNS3 →	-0.422	-0.434	.009	.003	3	3
HNSC	SP6 →	+0.791	+0.452	<.001	.001	3	3
BRCA	CBR3-AS1 →	-0.796	-0.754	.002	.001	3	3
HNSC	SMIM35 →	-0.631	-0.490	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,410 associations by consensus.

CHST11 vs PGAP4 — LSCC

Explore this scatter interactively →