CHST10

Across TCGA patient cohorts, CHST10 mutation is significantly associated with the RNA expression of many other genes, with 5,580 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHST10-associated genes across cancer lineages are ATP1B2, GCATP1, and CCL4. Each is linked with CHST10 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHST10-to-partner and partner-to-CHST10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP1B2 grouped by CHST10-low versus CHST10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST10→partner) and Y-score (partner→CHST10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP1B2 →	-0.732	-3.237	.001	<.001	3	3
UCEC	GCATP1 →	+0.353	+2.939	<.001	<.001	3	2
UCEC	CCL4 →	+1.033	+3.021	<.001	<.001	3	2
UCEC	SNRPD3 →	+0.351	+2.526	.001	.001	3	2
UCEC	POLR2F →	+0.092	+1.783	.002	.002	3	2
UCEC	PACSIN2 →	+0.566	+2.523	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,580 associations by consensus.

ATP1B2 by CHST10 expression — UCEC

Explore this box plot interactively →