CHST10

Across TCGA cell cohorts, CHST10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,292 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CHST10-associated GO terms across cancer lineages are rRNA transcription, Establishment of protein localization to organelle, and Nucleoside triphosphate biosynthetic process. Each is linked with CHST10 in more than 14 cancer types. Because this analysis shows association rather than direction, both CHST10-to-partner and partner-to-CHST10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA transcription grouped by CHST10-low versus CHST10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST10→partner) and Y-score (partner→CHST10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	rRNA transcription →	+0.092	+0.749	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Establishment of protein localization to organelle →	+0.061	+2.075	.002	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Nucleoside triphosphate biosynthetic process →	+0.093	+1.839	.001	<.001	3	12
BLOOD_Lymphoma	Transcription initiation at RNA polymerase I promoter →	+0.102	+1.315	<.001	<.001	3	12
URINARY_TRACT	Cell communication involved in cardiac conduction →	-0.247	-1.717	<.001	.002	3	12
BONE	tRNA transcription →	+0.093	+0.608	.001	.007	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,292 associations by consensus.

rRNA transcription by CHST10 expression — BONE

Explore this box plot interactively →