CHST10

Across TCGA cell cohorts, CHST10 mutation is significantly associated with the RNA expression of many other genes, with 103 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHST10-associated genes across cancer lineages are SSX7, OR5H2, and SYCN. Each is linked with CHST10 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHST10-to-partner and partner-to-CHST10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSX7 grouped by CHST10-low versus CHST10-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST10→partner) and Y-score (partner→CHST10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1
STOMACH	OR5H2 →	+0.276	+5.285	<.001	.003	3	1
BLOOD_Leukemia	SYCN →	+0.037	+4.539	<.001	.007	3	1
BLOOD_Leukemia	TDRD15 →	+0.360	+4.152	<.001	.009	3	1
LARGE_INTESTINE	TNP1 →	+0.079	+3.192	<.001	.002	3	1
LARGE_INTESTINE	MAGEB4 →	+0.009	+3.192	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

SSX7 by CHST10 expression — STOMACH

Explore this box plot interactively →