CHST1

Across TCGA patient cohorts, CHST1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,930 significant associations in total. OV shows the largest number of these associations.

The most reproducible CHST1-associated genes across cancer lineages are LARP4B, NLRC5, and MYD88. Each is linked with CHST1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHST1-to-partner and partner-to-CHST1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHST1 versus LARP4B in OV, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST1→partner) and Y-score (partner→CHST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LARP4B →	-0.929	-0.675	.001	.004	3	2
OV	NLRC5 →	-1.454	-0.698	.004	.003	3	2
OV	MYD88 →	-0.806	-0.774	.005	.003	3	2
BRCA	PARP14 →	-1.104	-0.976	.002	.001	3	2
BRCA	RCC2 →	-0.960	-0.912	.005	.003	3	2
BRCA	IPO9 →	-0.863	-0.917	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,930 associations by consensus.

CHST1 vs LARP4B — OV

Explore this scatter interactively →