CHST1

Across TCGA cell cohorts, CHST1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,461 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CHST1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Proton motive force-driven ATP synthesis. Each is linked with CHST1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CHST1-to-partner and partner-to-CHST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by CHST1-low versus CHST1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST1→partner) and Y-score (partner→CHST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of myoblast fusion →	+0.108	+0.571	<.001	.001	3	13
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.101	+0.560	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven ATP synthesis →	+0.067	+0.438	.004	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven mitochondrial ATP synthesis →	+0.067	+0.433	.005	.002	3	11
PANCREAS	Establishment of protein localization to organelle →	+0.039	+0.212	<.001	.009	3	11
OVARY	Regulation of myoblast fusion →	+0.098	+0.599	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,461 associations by consensus.

Negative regulation of myoblast fusion by CHST1 expression — OVARY

Explore this box plot interactively →