Across TCGA patient cohorts, CHROMR RNA expression is significantly associated with the protein abundance of many other proteins, with 12,485 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CHROMR-associated proteins across cancer lineages are CEP170, TBRG4, and HDAC2. Each is linked with CHROMR in more than 5 cancer types. Because this analysis shows association rather than direction, both CHROMR-to-partner and partner-to-CHROMR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHROMR→partner) and Y-score (partner→CHROMR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CEP170 →	+0.272	+0.322	.006	.007	3	6
COAD	TBRG4 →	-0.320	-0.386	<.001	<.001	3	5
GBM	HDAC2 →	+0.316	+0.332	.004	.005	2	5
PDAC	HIRIP3_S196 →	+0.740	+0.268	<.001	.004	3	4
CCRCC	MAP1A →	+0.437	+0.437	<.001	<.001	3	4
LUAD	MAP1B →	+0.807	+0.403	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,485 associations by consensus.

Exploration

CHROMR survival (RNA) · tumor vs normal (RNA) · all CHROMR data types