Across TCGA patient cohorts, CHRNG RNA expression is significantly associated with the protein abundance of many other proteins, with 10,862 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHRNG-associated proteins across cancer lineages are TMEM192_S230, ILF2, and HSP90B1. Each is linked with CHRNG in more than 3 cancer types. Because this analysis shows association rather than direction, both CHRNG-to-partner and partner-to-CHRNG results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNG→partner) and Y-score (partner→CHRNG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TMEM192_S230 →	-0.718	-0.354	.001	.001	3	4
GBM	ILF2 →	+0.299	+0.472	<.001	<.001	3	4
GBM	HSP90B1 →	-0.340	-0.368	<.001	<.001	3	4
LSCC	GMPPB →	-0.339	-0.529	<.001	<.001	3	4
COAD	DMXL1 →	-0.284	-0.045	.002	.003	3	4
LSCC	ADAR →	+0.305	+0.450	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,862 associations by consensus.

Exploration

CHRNG survival (RNA) · tumor vs normal (RNA) · all CHRNG data types