CHRND

Across TCGA patient cohorts, CHRND protein abundance is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CHRND-associated genes across cancer lineages are PBX4, CCL7, and IL23A. Each is linked with CHRND in more than 1 cancer types. Because this analysis shows association rather than direction, both CHRND-to-partner and partner-to-CHRND results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRND versus PBX4 in HNSC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRND→partner) and Y-score (partner→CHRND) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PBX4 →	-0.993	-1.431	.003	<.001	3	1
HNSC	CCL7 →	-1.291	-1.799	.009	.002	3	1
HNSC	IL23A →	-2.054	-1.484	<.001	<.001	3	1
HNSC	CAP2 →	+0.957	+1.264	.009	.004	3	1
HNSC	STIL →	-1.008	-1.617	.001	.001	3	1
HNSC	AUNIP →	-0.891	-1.474	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

CHRND vs PBX4 — HNSC

Explore this scatter interactively →