CHRND

Across TCGA cell cohorts, CHRND RNA expression is significantly associated with the go_rna of many other GO terms, with 2,310 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CHRND-associated GO terms across cancer lineages are Regulation of body fluid levels, Cytoskeleton-dependent cytokinesis, and Mitotic cytokinesis. Each is linked with CHRND in more than 5 cancer types. Because this analysis shows association rather than direction, both CHRND-to-partner and partner-to-CHRND results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of body fluid levels grouped by CHRND-low versus CHRND-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRND→partner) and Y-score (partner→CHRND) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of body fluid levels →	-0.064	-0.030	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Cytoskeleton-dependent cytokinesis →	+0.066	+0.040	<.001	.005	3	6
UPPER_AERODIGESTIVE_TRACT	Mitotic cytokinesis →	+0.071	+0.026	.001	.008	3	6
BLOOD_Leukemia	Regulation of stem cell differentiation →	+0.068	+0.020	<.001	.005	3	5
SOFT_TISSUE	Regulatory ncRNA-mediated gene silencing →	+0.077	+2.885	<.001	<.001	3	5
BLOOD_Lymphoma	'de novo' IMP biosynthetic process →	+0.105	+0.041	<.001	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,310 associations by consensus.

Regulation of body fluid levels by CHRND expression — OVARY

Explore this box plot interactively →