CHRNB1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CHRNB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,186 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CHRNB1-associated proteins across cancer lineages are ANKFY1, LLGL1, and INPP4A. Each is linked with CHRNB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHRNB1-to-partner and partner-to-CHRNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRNB1 versus ANKFY1 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNB1→partner) and Y-score (partner→CHRNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMANKFY1 →+0.295+0.567<.001<.00135
GBMLLGL1 →+0.311+0.309<.001<.00135
HNSCINPP4A →+0.218+0.568<.001<.00134
OVDVL2 →+0.290+0.652.004.00134
OVAKAP1_S592 →-0.766-0.690.001<.00134
BRCAYWHAE →+0.223+0.531.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,186 associations by consensus.

CHRNB1 vs ANKFY1 — GBM

Per-sample scatter of CHRNB1 vs ANKFY1 in GBM (Pearson r = 0.51).

Explore this scatter interactively →

Exploration