CHRNA9

Across TCGA patient cohorts, CHRNA9 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,020 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHRNA9-associated proteins across cancer lineages are P4HA2, ALDH5A1, and TPI1_S80. Each is linked with CHRNA9 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHRNA9-to-partner and partner-to-CHRNA9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRNA9 versus P4HA2 in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNA9→partner) and Y-score (partner→CHRNA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	P4HA2 →	+0.906	+1.905	<.001	<.001	3	5
GBM	ALDH5A1 →	-0.604	-1.740	<.001	<.001	3	5
LUAD	TPI1_S80 →	+0.674	+1.574	<.001	<.001	3	4
CCRCC	SERPINE1 →	+1.097	+0.058	<.001	<.001	3	4
GBM	SMARCC2 →	-0.254	-1.255	.001	<.001	3	4
HNSC	COL5A2 →	+0.627	+0.580	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,020 associations by consensus.

CHRNA9 vs P4HA2 — GBM

Explore this scatter interactively →