CHRNA9

Across TCGA cell cohorts, CHRNA9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,135 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHRNA9-associated GO terms across cancer lineages are Digestive system process, Regulation of cell cycle G1/S phase transition, and Regulation of digestive system process. Each is linked with CHRNA9 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHRNA9-to-partner and partner-to-CHRNA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Digestive system process grouped by CHRNA9-low versus CHRNA9-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNA9→partner) and Y-score (partner→CHRNA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Digestive system process →	-0.057	-0.116	.003	.004	3	6
BLOOD_Leukemia	Regulation of cell cycle G1/S phase transition →	+0.051	+0.813	<.001	<.001	3	5
CNS	Regulation of digestive system process →	-0.081	-1.322	.003	.005	3	5
BLOOD_Lymphoma	Thyroid hormone metabolic process →	-0.149	-0.122	<.001	.007	3	4
BLOOD_Leukemia	Regulation of phosphatidylcholine metabolic process →	-0.138	-0.975	<.001	<.001	3	4
BLOOD_Leukemia	Regulation of G1/S transition of mitotic cell cycle →	+0.050	+0.837	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,135 associations by consensus.

Digestive system process by CHRNA9 expression — BLOOD_Lymphoma

Explore this box plot interactively →