CHRNA7

Across TCGA patient cohorts, CHRNA7 RNA expression is significantly associated with the RNA expression of many other genes, with 18,704 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible CHRNA7-associated genes across cancer lineages are CHRFAM7A, HMG20A, and IREB2. Each is linked with CHRNA7 in more than 32 cancer types. Because this analysis shows association rather than direction, both CHRNA7-to-partner and partner-to-CHRNA7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRNA7 versus CHRFAM7A in PCPG, with a Pearson correlation of 0.84.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNA7→partner) and Y-score (partner→CHRNA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PCPG	CHRFAM7A →	+0.905	+1.747	<.001	<.001	3	33
UCS	HMG20A →	+1.609	+0.381	<.001	.004	3	29
UVM	IREB2 →	+1.023	+0.143	<.001	.002	3	29
PCPG	NIPA2 →	+1.153	+1.014	<.001	<.001	3	29
THYM	SEC24C →	+1.439	+0.268	<.001	<.001	3	28
ACC	RTL6 →	+1.200	+1.172	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,704 associations by consensus.

CHRNA7 vs CHRFAM7A — PCPG

Explore this scatter interactively →