CHRNA7

Across TCGA patient cohorts, CHRNA7 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,318 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHRNA7-associated proteins across cancer lineages are PAFAH2, LDHA_Y10, and MAP7D1_S273. Each is linked with CHRNA7 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHRNA7-to-partner and partner-to-CHRNA7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRNA7 versus PAFAH2 in UCEC, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNA7→partner) and Y-score (partner→CHRNA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PAFAH2 →	-0.342	-0.330	<.001	.003	3	3
PDAC	LDHA_Y10 →	-0.702	-0.303	<.001	.009	3	3
HNSC	MAP7D1_S273 →	-0.708	-0.484	.002	.001	3	3
BRCA	LYPLA1 →	-0.317	-0.067	<.001	<.001	3	3
UCEC	GOLGA2 →	-0.247	-0.347	.001	.002	3	3
BRCA	TKFC →	-0.317	-0.066	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,318 associations by consensus.

CHRNA7 vs PAFAH2 — UCEC

Explore this scatter interactively →