CHRNA10

Across TCGA patient cohorts, CHRNA10 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,813 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHRNA10-associated proteins across cancer lineages are EEA1_S52, EIF4EBP2_S65, and SP100_S410. Each is linked with CHRNA10 in more than 3 cancer types. Because this analysis shows association rather than direction, both CHRNA10-to-partner and partner-to-CHRNA10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRNA10 versus EEA1_S52 in PDAC, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNA10→partner) and Y-score (partner→CHRNA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	EEA1_S52 →	-0.720	-0.333	.001	<.001	3	4
CCRCC	EIF4EBP2_S65 →	+0.624	+0.353	<.001	<.001	3	4
OV	SP100_S410 →	-1.071	-0.271	<.001	.006	3	4
HNSC	VPS13D_S2671 →	-0.920	-0.501	<.001	<.001	3	4
LSCC	RBM10_S797 →	+0.598	+0.564	<.001	<.001	3	4
GBM	TAF15_S438 →	+0.884	+0.487	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,813 associations by consensus.

CHRNA10 vs EEA1_S52 — PDAC

Explore this scatter interactively →