CHRNA10

Across TCGA patient cohorts, CHRNA10 mutation is significantly associated with the RNA expression of many other genes, with 375 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHRNA10-associated genes across cancer lineages are LINC00904, RNA5SP358, and TMEM38B. Each is linked with CHRNA10 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHRNA10-to-partner and partner-to-CHRNA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00904 grouped by CHRNA10-low versus CHRNA10-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNA10→partner) and Y-score (partner→CHRNA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC00904 →	+0.049	+3.159	<.001	.008	3	3
LUAD	RNA5SP358 →	+0.220	+4.399	<.001	.008	3	2
UCEC	TMEM38B →	+0.863	+2.818	<.001	.001	3	2
UCEC	LINC00544 →	+0.090	+2.048	.001	.007	3	2
UCEC	RRP8 →	+0.362	+2.536	.003	.009	3	2
COAD	SNORD116-26 →	+0.398	+4.212	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 375 associations by consensus.

LINC00904 by CHRNA10 expression — SKCM

Explore this box plot interactively →