CHRM3

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CHRM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,989 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CHRM3-associated proteins across cancer lineages are MYO1G, LRRFIP1, and MAP2. Each is linked with CHRM3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHRM3-to-partner and partner-to-CHRM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRM3 versus MYO1G in GBM, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRM3→partner) and Y-score (partner→CHRM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMYO1G →-0.515-1.062<.001<.00135
HNSCLRRFIP1 →-0.361-1.387<.001<.00135
LSCCMAP2 →+0.691+0.821<.001<.00135
LSCCPSMB10 →-0.405-1.162<.001<.00134
LSCCZCCHC3 →+0.569+1.232<.001<.00134
HNSCZNF462 →+0.569+1.108.001.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,989 associations by consensus.

CHRM3 vs MYO1G — GBM

Per-sample scatter of CHRM3 vs MYO1G in GBM (Pearson r = -0.37).

Explore this scatter interactively →

Exploration