CHRM1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CHRM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,703 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHRM1-associated proteins across cancer lineages are NAXD, ABLIM1, and MAPRE2. Each is linked with CHRM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CHRM1-to-partner and partner-to-CHRM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRM1 versus NAXD in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRM1→partner) and Y-score (partner→CHRM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMNAXD →+0.246+0.731<.001<.00134
BRCAABLIM1 →+0.362+0.491<.001.00734
BRCAMAPRE2 →+0.455+0.861.001.00134
GBMSTXBP6 →+0.896+1.128<.001<.00134
GBMXRCC6_S520 →-0.584-0.731.009.00833
COADAAR2 →-0.238-0.336<.001.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,703 associations by consensus.

CHRM1 vs NAXD — GBM

Per-sample scatter of CHRM1 vs NAXD in GBM (Pearson r = 0.40).

Explore this scatter interactively →

Exploration