CHRM1

Across TCGA patient cohorts, CHRM1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,266 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHRM1-associated genes across cancer lineages are SOX10, SEPTIN3, and NEFH. Each is linked with CHRM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHRM1-to-partner and partner-to-CHRM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRM1 versus SOX10 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRM1→partner) and Y-score (partner→CHRM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SOX10 →	+1.869	+0.976	<.001	<.001	3	1
GBM	SEPTIN3 →	+0.847	+0.631	.001	<.001	3	1
GBM	NEFH →	+1.308	+0.662	<.001	<.001	3	1
GBM	RASD2 →	+0.867	+0.995	<.001	<.001	3	1
GBM	SYNGR1 →	+0.805	+0.569	<.001	.001	3	1
GBM	PNPLA5 →	+0.388	+0.782	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,266 associations by consensus.

CHRM1 vs SOX10 — GBM

Explore this scatter interactively →