CHRDL1

Across TCGA patient cohorts, CHRDL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,540 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CHRDL1-associated proteins across cancer lineages are AOC3, HSPB7, and TLN1. Each is linked with CHRDL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CHRDL1-to-partner and partner-to-CHRDL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRDL1 versus AOC3 in BRCA, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRDL1→partner) and Y-score (partner→CHRDL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AOC3 →	+0.939	+1.802	<.001	<.001	3	9
HNSC	HSPB7 →	+0.898	+1.171	<.001	<.001	3	9
UCEC	TLN1 →	+0.538	+1.865	<.001	<.001	3	8
CCRCC	TNXB →	+0.811	+1.473	<.001	.008	3	8
UCEC	PPP1R12B →	+0.858	+1.312	<.001	<.001	3	8
UCEC	PRELP →	+0.898	+1.537	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,540 associations by consensus.

CHRDL1 vs AOC3 — BRCA

Explore this scatter interactively →