CHRDL1

Across TCGA patient cohorts, CHRDL1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,749 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CHRDL1-associated genes across cancer lineages are CORO2B, RECK, and PTGIS. Each is linked with CHRDL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHRDL1-to-partner and partner-to-CHRDL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRDL1 versus CORO2B in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRDL1→partner) and Y-score (partner→CHRDL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CORO2B →	+0.866	+1.148	<.001	<.001	3	6
OV	RECK →	+0.794	+1.040	<.001	<.001	3	6
HNSC	PTGIS →	+1.840	+0.738	<.001	<.001	3	6
BRCA	AOC3 →	+1.788	+1.214	<.001	<.001	3	6
OV	FBLN5 →	+1.701	+1.485	<.001	<.001	3	6
OV	ABCA8 →	+1.265	+1.050	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,749 associations by consensus.

CHRDL1 vs CORO2B — UCEC

Explore this scatter interactively →