CHPF2

Across TCGA pan-cancer cohorts, CHPF2 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CHPF2 data layer compared with 27 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher CHPF2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CHPF2 expression acts as an unfavorable survival marker.

LIHC, SCLC, and LGG are the cancer types where CHPF2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.079	0.774	<.001	30	view →
SCLC	OS	Median	All	0.055	0.708	<.001	12	view →
LGG	OS	Median	All	0.238	0.799	.002	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CHPF2–LIHC (OS)

Open the LIHC breakdown →