CHPF2

Across TCGA patient cohorts, CHPF2 mutation is significantly associated with the RNA expression of many other genes, with 4,743 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHPF2-associated genes across cancer lineages are RNU1-35P, MIR3189, and UBE2FP2. Each is linked with CHPF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHPF2-to-partner and partner-to-CHPF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-35P grouped by CHPF2-low versus CHPF2-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHPF2→partner) and Y-score (partner→CHPF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU1-35P →	+1.036	+3.816	<.001	.002	3	2
UCEC	MIR3189 →	+0.892	+1.777	.003	.002	3	2
SKCM	UBE2FP2 →	+0.084	+3.076	.009	.005	3	2
LUAD	RNA5SP358 →	+0.324	+5.984	<.001	.002	3	2
LUAD	OR2AI1P →	+0.058	+5.798	.006	.003	3	2
LUAD	MIR8053 →	+0.589	+5.343	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,743 associations by consensus.

RNU1-35P by CHPF2 expression — STAD

Explore this box plot interactively →