CHP2

Across TCGA cell cohorts, CHP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,016 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHP2-associated GO terms across cancer lineages are Termination of RNA polymerase II transcription, Post-transcriptional gene silencing, and Succinyl-CoA biosynthetic process. Each is linked with CHP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHP2-to-partner and partner-to-CHP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Termination of RNA polymerase II transcription grouped by CHP2-low versus CHP2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHP2→partner) and Y-score (partner→CHP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Termination of RNA polymerase II transcription →	+0.090	+0.065	.002	.008	3	5
SOFT_TISSUE	Post-transcriptional gene silencing →	+0.071	+0.034	<.001	.009	3	5
OESOPHAGUS	Succinyl-CoA biosynthetic process →	+0.108	+2.296	.008	.008	3	4
LARGE_INTESTINE	Positive regulation of odontoblast differentiation →	-0.127	-1.594	<.001	.001	3	4
LARGE_INTESTINE	Positive regulation of neuroepithelial cell differentiation →	-0.127	-1.594	<.001	.001	3	4
OVARY	Cellular respiration →	+0.061	+0.262	.003	.003	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,016 associations by consensus.

Termination of RNA polymerase II transcription by CHP2 expression — SOFT_TISSUE

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