CHP1P1

Across TCGA pan-cancer cohorts, CHP1P1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CHP1P1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CHP1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CHP1P1 is over-expressed in tumor, although a few such as KIRP and LUSC show the opposite, repressed pattern.

BRCA, LUAD, and KIRP are the cancer types where CHP1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CHP1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.135	.026	4	view →
LUAD	Male	All	+0.420	.045	2	view →
KIRP	Female	II,III,IV	−0.118	.043	2	view →
LUSC	All	All	−0.058	.013	2	view →
THCA	Female	III,IV	+0.066	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

CHP1P1–BRCA

Open the BRCA breakdown →