Across TCGA pan-cancer cohorts, CHP1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CHP1 data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in thyroid carcinoma (THCA), where higher CHP1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CHP1 expression acts as an unfavorable survival marker.

THCA and UCEC are the cancer types where CHP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Median	All	0.040	0.828	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: CHP1 tumor-vs-normal RNA expression · all CHP1 data types