Across TCGA patient cohorts, CHP1 mutation is significantly associated with the RNA expression of many other genes, with 236 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHP1-associated genes across cancer lineages are ABHD17AP7, RNU6-441P, and MIR5186. Each is linked with CHP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHP1-to-partner and partner-to-CHP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHP1→partner) and Y-score (partner→CHP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	ABHD17AP7 →	+0.059	+7.640	<.001	.009	3	2
UCEC	RNU6-441P →	+0.162	+4.148	<.001	.006	3	2
SKCM	MIR5186 →	+0.194	+4.469	<.001	.006	3	2
UCEC	MIR5188 →	+0.718	+2.650	<.001	.001	3	2
SKCM	MTND3P16 →	+0.158	+4.199	<.001	.009	3	2
BRCA	MIR6853 →	+0.364	+9.057	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 236 associations by consensus.

Exploration

CHP1 survival (RNA) · tumor vs normal (RNA) · all CHP1 data types