CHORDC1

Across TCGA pan-cancer cohorts, CHORDC1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CHORDC1 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CHORDC1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CHORDC1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

COAD, CCRCC, and LUAD are the cancer types where CHORDC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.910	1.000	.010	36	view →
CCRCC	OS	Median	II,III,IV	0.277	0.917	.007	25	view →
LUAD	OS	Tertile	All	0.597	0.848	.008	22	view →
UCEC	DFS	Median	III,IV	0.904	0.445	.037	4	view →
PDAC	OS	Tertile	II,III,IV	0.270	0.456	.015	4	view →
HNSC	OS	Median	III,IV	0.787	0.586	.032	3	view →
GBM	OS	Quartile	All	0.376	0.610	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CHORDC1–COAD (DFS)

Open the COAD breakdown →