CHORDC1

Across TCGA patient cohorts, CHORDC1 mutation is significantly associated with the RNA expression of many other genes, with 858 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHORDC1-associated genes across cancer lineages are MIR6078, RNU6-370P, and NPM1P28. Each is linked with CHORDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHORDC1-to-partner and partner-to-CHORDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6078 grouped by CHORDC1-low versus CHORDC1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHORDC1→partner) and Y-score (partner→CHORDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6078 →	+0.672	+6.016	<.001	.002	3	2
BRCA	RNU6-370P →	+0.363	+5.070	.003	.008	3	2
BRCA	NPM1P28 →	+0.054	+5.409	.001	.005	3	2
UCEC	RNU6-787P →	+0.232	+2.232	.003	.007	3	2
BLCA	TMX2-CTNND1 →	+0.098	+3.241	.003	.009	3	2
SKCM	RNA5SP125 →	+0.426	+6.080	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 858 associations by consensus.

MIR6078 by CHORDC1 expression — BRCA

Explore this box plot interactively →