CHORDC1

Across TCGA cell cohorts, CHORDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,688 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHORDC1-associated GO terms across cancer lineages are CENP-A containing chromatin assembly, Kinetochore assembly, and Centromeric sister chromatid cohesion. Each is linked with CHORDC1 in more than 16 cancer types. Because this analysis shows association rather than direction, both CHORDC1-to-partner and partner-to-CHORDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENP-A containing chromatin assembly grouped by CHORDC1-low versus CHORDC1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHORDC1→partner) and Y-score (partner→CHORDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CENP-A containing chromatin assembly →	+0.204	+1.036	.002	.001	3	17
BLOOD_Myeloma	Kinetochore assembly →	+0.164	+1.108	.009	.001	3	16
KIDNEY	Centromeric sister chromatid cohesion →	+0.152	+0.961	.002	.005	2	17
KIDNEY	Protein localization to condensed chromosome →	+0.177	+1.142	<.001	<.001	3	16
SOFT_TISSUE	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.096	+1.254	<.001	<.001	3	16
KIDNEY	Chromosome localization →	+0.116	+1.065	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,688 associations by consensus.

CENP-A containing chromatin assembly by CHORDC1 expression — BLOOD_Myeloma

Explore this box plot interactively →