CHN2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CHN2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,485 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHN2-associated genes across cancer lineages are GDPD3, MYH14, and CDR2L. Each is linked with CHN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHN2-to-partner and partner-to-CHN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHN2 versus GDPD3 in UCEC, with a Pearson correlation of -0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHN2→partner) and Y-score (partner→CHN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGDPD3 →-0.704-0.961.001.00431
UCECMYH14 →-1.857-0.794.003.00331
UCECCDR2L →-1.165-0.782<.001.00531
UCECATP10B →-1.664-0.897<.001<.00131
UCECPCDHB8 →-1.398-1.001.005.00131
UCECCDK2 →-0.555-0.828.002.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,485 associations by consensus.

CHN2 vs GDPD3 — UCEC

Per-sample scatter of CHN2 vs GDPD3 in UCEC (Pearson r = -0.77).

Explore this scatter interactively →

Exploration