CHN2

Across TCGA patient cohorts, CHN2 mutation is significantly associated with the RNA expression of many other genes, with 1,984 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHN2-associated genes across cancer lineages are RNA5SP419, MIR4266, and TYMSP2. Each is linked with CHN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHN2-to-partner and partner-to-CHN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by CHN2-low versus CHN2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHN2→partner) and Y-score (partner→CHN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.538	+1.684	<.001	.007	3	3
GBM	MIR4266 →	+0.564	+4.857	<.001	.005	3	2
LUAD	TYMSP2 →	+0.102	+3.928	<.001	.002	3	2
GBM	DIAPH3-AS1 →	+0.240	+4.857	<.001	.005	3	2
GBM	BMS1P19 →	+0.103	+4.857	<.001	.005	3	2
HNSC	CCDC12P1 →	+0.064	+5.351	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,984 associations by consensus.

RNA5SP419 by CHN2 expression — UCEC

Explore this box plot interactively →