CHMP5

Across TCGA patient cohorts, CHMP5 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,882 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHMP5-associated proteins across cancer lineages are DNAJA1, UBAP2, and NFX1. Each is linked with CHMP5 in more than 7 cancer types. Because this analysis shows association rather than direction, both CHMP5-to-partner and partner-to-CHMP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP5 versus DNAJA1 in LSCC, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP5→partner) and Y-score (partner→CHMP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DNAJA1 →	+0.317	+0.660	<.001	<.001	3	8
HNSC	UBAP2 →	+0.480	+1.052	<.001	<.001	3	6
LSCC	NFX1 →	+0.354	+0.611	<.001	<.001	3	5
BRCA	PDIA6 →	-0.317	-0.448	<.001	<.001	3	5
COAD	CDC37L1 →	+0.330	+0.646	.002	.001	3	5
LSCC	APTX →	+0.325	+0.568	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,882 associations by consensus.

CHMP5 vs DNAJA1 — LSCC

Explore this scatter interactively →