CHMP4BP1

Across TCGA cell cohorts, CHMP4BP1 protein abundance is significantly associated with the drug of many other genes, with 40 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHMP4BP1-associated genes across cancer lineages are NG-25, Pelitinib, and TPCA-1. Each is linked with CHMP4BP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHMP4BP1-to-partner and partner-to-CHMP4BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NG-25 grouped by CHMP4BP1-low versus CHMP4BP1-high in BLOOD_Leukemia.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP4BP1→partner) and Y-score (partner→CHMP4BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NG-25 →	-0.981	-1.502	.040	.002	3	2
BLOOD_Leukemia	Pelitinib →	-0.626	-1.263	.026	.009	3	2
BLOOD_Leukemia	TPCA-1 →	-0.819	-1.501	.034	.002	3	2
BLOOD_Leukemia	CD532 →	-0.644	-1.317	.002	.018	3	2
BLOOD_Leukemia	AZD1208 →	-0.446	-1.316	.022	.012	3	1
BLOOD_Leukemia	Ponatinib →	-1.337	-1.352	.019	.013	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

NG-25 by CHMP4BP1 expression — BLOOD_Leukemia

Explore this box plot interactively →