CHMP4A

Across TCGA patient cohorts, CHMP4A protein abundance is significantly associated with the RNA expression of many other genes, with 6,890 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHMP4A-associated genes across cancer lineages are PSME2, GPLD1, and ALDH5A1. Each is linked with CHMP4A in more than 3 cancer types. Because this analysis shows association rather than direction, both CHMP4A-to-partner and partner-to-CHMP4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP4A versus PSME2 in HNSC, with a Pearson correlation of 0.19.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP4A→partner) and Y-score (partner→CHMP4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PSME2 →	+0.772	+0.262	.005	.001	3	4
HNSC	GPLD1 →	-0.757	-0.290	<.001	.001	3	4
HNSC	ALDH5A1 →	-0.664	-0.306	.001	<.001	3	4
LUAD	ZNF682 →	-0.992	-0.492	<.001	<.001	3	4
GBM	UNKL →	-0.454	-0.352	<.001	<.001	3	4
CCRCC	CUBN →	-1.050	-0.170	.005	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,890 associations by consensus.

CHMP4A vs PSME2 — HNSC

Explore this scatter interactively →