CHMP2B

Across TCGA patient cohorts, CHMP2B RNA expression is significantly associated with the protein abundance of many other proteins, with 9,578 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CHMP2B-associated proteins across cancer lineages are ZC3H18_S534, ARF4, and OXSR1. Each is linked with CHMP2B in more than 2 cancer types. Because this analysis shows association rather than direction, both CHMP2B-to-partner and partner-to-CHMP2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP2B versus ZC3H18_S534 in LUAD, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP2B→partner) and Y-score (partner→CHMP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZC3H18_S534 →	-0.334	-0.288	.001	.001	3	3
PDAC	ARF4 →	+0.297	+0.302	.001	<.001	3	3
PDAC	OXSR1 →	+0.261	+0.398	<.001	<.001	3	3
LSCC	CHMP2B_S199 →	+0.394	+0.339	<.001	<.001	3	3
PDAC	MRPL47 →	-0.430	-0.406	<.001	<.001	3	3
GBM	SRRM1_S616 →	-0.305	-0.292	.005	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,578 associations by consensus.

CHMP2B vs ZC3H18_S534 — LUAD

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